Application of Acetovanillone？

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Acetovanillone is a synthetic raw material for various psychotropic drugs and various new antimalarial drugs, and is often used as a cardiotonic and diuretic in medicine. Vanillyl ethyl ketone is currently recognized as a specific inhibitor of nicotinamide adenine dinucleotide oxidase, nicotinamide adenine dinucleotide phosphate (NADPH) oxidase and xanthine oxidase are the main free radicals during myocardial reperfusion Sources from Chemicalbook, thus inhibiting their activity and reducing free radical generation may alleviate reperfusion injury. In this experiment, the use of the NADPH oxidase inhibitor vanillyl ethyl ketone can exert a protective effect on reperfused rat myocardium, which is related to the inhibition of NADPH oxidase activity and the reduction of superoxide anion and peroxynitrite mediated by it. generation of free radicals. Acetovanillone can protect the myocardium by inhibiting the activity of NADPH oxidase, reducing the free radical generation and neutrophil infiltration mediated by it, protecting cardiac function, reducing myocardial cell apoptosis and effectively treating myocardial reperfusion injury. Acetovanillone, also known as vanilla acetone, acetyl vanillone, has a weak vanilla odor. It is not only used in the fragrance industry but also an important organic synthesis raw material. It can be used to synthesize the psychoactive drug iloperidone and a variety of new antimalarial drugs. At the same time, Chemicalbook is a commonly used antioxidant and is currently recognized as a specific nicotinamide adenine dinucleotide oxidase inhibitor. It is also commonly used as a cardiotonic and diuretic in medicine. Acetovanillone can be used in the fragrance industry and is also an important organic synthesis raw material. It can be used to synthesize the psychoactive drug iloperidone and a variety of new antimalarial drugs. It is also a commonly used antioxidant, a currently recognized specific nicotinamide adenine dinucleotide oxidase inhibitor, and is also commonly used as a cardiotonic and diuretic in medicine.

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