Indications for Cefuroxime？

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Cefuroxime is white crystal in nature, [α] is +63.7° (C=1.0, 0.2mol/L phosphate buffer pH=7). UV absorption maximum (pH=6 phosphate buffer): 274 nm (ε17600). Cefuroxime Sodium: C16H15N4aO8SNa. [56 Chemicalbook 238-63-2]. White solid, easily soluble in water or buffer solution, soluble in methanol, very slightly soluble in ethyl alcohol, ether, octanol, benzene or chloroform, the solubility in water is 500mg/2.5ml. pKa (water): 2.5; pKa (Z. methylformamide): 5.1. [α] D20+60° (C=0.91, water). Cefuroxime is suitable for the treatment of the following infections caused by sensitive bacteria: respiratory system and ENT infections (such as pharyngitis, tonsillitis, otitis media, sinusitis, acute and chronic bronchitis, bronchiectasis complicated infection, bacterial pneumonia, lung abscess, postoperative Pulmonary infections, acute maxillary sinusitis); urogenital infections (eg, pelvic inflammatory disease, pyelonephritis, cystitis, asymptomatic bacteriuria, gonorrhea); bone and joint infections (eg, osteomyelitis and septic arthritis); Skin and soft tissue infections (such as cellulitis, peritonitis, erysipelas, impetigo and wound infections). It is also used to prevent surgical infections (eg, in abdominal, pelvic and orthopedic surgery, cardiac, pulmonary, esophageal and vascular surgery, and in total joint replacement surgery). Others, can be used for the treatment of sepsis, meningitis, and also for female simple gonorrhea proctitis caused by Neisseria gonorrhoeae, which does not produce penicillinase, and early erythema migrans (Lyme disease) caused by Borrelia burgdorferi.

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