Hydrogen Production Machine
The work principle ?
Biological effects of H2.H2 exhibiting selective antioxidant and anti-inflammatory activities and modulating ER stress, mitochondria, and immune function. H2 selectively scavenged OH and ONOO-, up-regulated NRF-2 and HO-1, and down-regulated the expressions of proinflammatory and inflammatory cytokines TNF-A, NF-KB, INF-Y, Fas, FasL, IL-1A, IL-1β, IL-6, IL-8 and IL10.Down-regulated expression of endoplasmic reticulum stress-related factors GRP78 and TRAF2. H2 also reduces Mir-210 and activates OXPHOS in mitochondria. H2 increased CD4+CD25+Foxp3+Treg cells and maintained Thl/Th2 balance.
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