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Pharmaceutical raw materials Hydrochloride Glucosamine hydrochloride is a occurring amino monosaccharide, an essential component for the synthesis of proteoglycans in cartilage matrix. It is typically extracted from crabs and shellfish, and can also be obtained through chemical synthesis. Its chemical name is: 2 - amino - 2 - deoxy - D- (+ ) glucopyranose hydrochloride. Its molecular formula is C6H13NO5・HCl, with a relative molecular mass of 21.63.
Functions
1. Protecting Articular Cartilage Glucosamine hydrochloride can stimulate chondrocytes to proteoglycans with normal polymeric structures, enhancing the repair capability of chondrocytes, and promoting the repair and reconstruction of the cartilage.
It can inhibit the activity of enzymes that damage cartilage, such as collagenase and phospholipase A2, reducing the destruction of cartilage. these actions, glucosamine hydrochloride can help slow the progression of osteoarthritis, alleviating symptoms such as joint pain, swelling, and stiffness
2. Antibacterial ingredients Effects
Although glucosamine hydrochloride is not a typical anti-inflammatory drug, it can reduce joint inflammatory reactions to some extent. It exert anti-inflammatory effects by reducing the synthesis of inflammatory mediators such as prostaglandin E2, and by inhibiting the aggregation and activation of inflammatory cells
3. Other Effects Glucosamine hydrochloride has certain preventive and
therapeutic effects on osteoporosis. It can promote the activity of osteoblast, increasing bone density. Additionally, glucosamine hydrochloride may have some regulatory effects on the immune system.
Applications
1. Pharmaceutical Chemicals Field
It mainly used to treat osteoarthritis, alleviating joint pain and improving joint function. It is usually administered orally, such as in capsules or tablets. For with mild to moderate osteoarthritis, glucosamine hydrochloride can be used alone or in combination with non-steroidal anti-inflammatory drugs (NSIDs). In some cases, it can also be used in the rehabilitation treatment after joint injuries.
2. Food Additives Field
As a raw material for health foods it is used to maintain joint health and prevent the occurrence of osteoarthritis. In conclusion, glucosamine hydrochloride plays an important role in protectingicular cartilage, treating osteoarthritis, and maintaining joint health. It is widely used in both the medical and health food fields. However, its use be guided by doctors or professionals based on specific circumstances.
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